Efficacy of Autologous Peripheral Blood Stem CellTransplantation in POEMS Syndrome with Polyneuropathy
スポンサーリンク
概要
- 論文の詳細を見る
POEMS syndrome (POEMS) is a rare multi-system disease which is typically associated with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes. We report herein a case of POEMS with progressive polyneuropathy resistant to high-dose intravenous immunoglobulin therapy who experienced improvement in polyneuropathy after the administration of high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation. Improvements in polyneuropathy remain despite recognition of monoclonal gammopathy by immunofixation as of 1 year after treatment. We demonstrated that autologous peripheral blood stem cell transplantation can improve clinical symptoms and signs due to polyneuropathy in POEMS even without achieving complete remission.
著者
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KONISHI Takashi
the Department of Cardiology, Tenri Hospital
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Konishi Takashi
The Department of Neurology, Shizuoka Red Cross Hospital
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Imai Noboru
The Department of Neurology, Shizuoka Red Cross Hospital
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Kitamura Eiji
The Department of Neurology, Shizuoka Red Cross Hospital
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Tachibana Takayoshi
the Department of Hematology, Shizuoka Red Cross Hospital
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Suzuki Youji
The Department of Neurology, Shizuoka Red Cross Hospital
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Serizawa Masahiro
The Department of Neurology, Shizuoka Red Cross Hospital
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Okabe Takashi
The Department of Neurology, Shizuoka Red Cross Hospital
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Fujita Hiroyuki
the Department of Hematology, Shizuoka Red Cross Hospital
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