Cerebral Pachyleptomeningitis Associated with MPO-ANCA Induced by PTU Therapy

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概要

• 論文の詳細を見る

• A 34-year-old woman with hyperthyroidism, who had been previously treated with propylthiouracil (PTU) is reported. She was admitted because of clumsiness in her left hand and abnormal behavior. A neurological examination demonstrated impairment of higher cortical function, and weakness and hyperreflexia of the left leg. An MRI scan with gadolinium enhancement showed pachyleptomeningeal thickening in the right frontoparietal lobe. Blood tests revealed a high MPO-ANCA titer of 122 EU (normal:<10 EU). After steroid administration, the neurological symptoms and the MRI findings improved markedly. This is the first report of PTU-induced cerebral pachyleptomeningitis associated with a high serum MPO-ANCA titer.

• 社団法人 日本内科学会の論文

著者

• IKEDA Eiji

  Pathology, Keio University School of Medicine

• Ikeda Eiji

  Pathology School Of Medicine Keio University

• Tanahashi Norio

  Neurology, Keio University School of Medicine

• Shiraishi Junichi

  Pathology, Keio University School of Medicine

• Abe Takato

  Neurology, Keio University School of Medicine

• Nogawa Shigeru

  Neurology, Keio University School of Medicine

• Suzuki Norihiro

  Neurology, Keio University School of Medicine

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• Cerebral Pachyleptomeningitis Associated with MPO-ANCA Induced by PTU Therapy

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