Glucocorticoid Therapy Ameliorated Hypoglycemia in Insulin-like Growth Factor-II-producing Solitary Fibrous Tumor
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概要
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A 54-year-old man with a past history of multi-operation for solitary fibrous tumor was hospitalized for hypoglycemia. Computed tomography demonstrated multiple tumors in the liver but not in the pancreas. His serum insulin-like growth factor (IGF)-II level was normal, but immunoblot analysis and immunohistochemistry revealed a high molecular weight form of IGF-II in the serum and tumor. Surgical resection was impossible, because of tumor dissemination. Hypoglycemia was repeated despite infusion of glucose and glucagon. Glucocorticoid dramatically and continuously abolished hypoglycemia. In cases of inoperable IGF-II-producing tumor, glucocorticoid therapy may be promising for hypoglycemia.
著者
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Yoshiji Hitoshi
Third Department Of Internal Medicine Nara Medical University
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NAKAJIMA YOSHIYUKI
First Department of Surgery, Nara Medical University
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KOJIMA HIDEYUKI
Third Department of Internal Medicine, Nara Medical University
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NAKAMURA TAKASHI
First Dept. of Intern. Med., Tohoku Univ. school of Med.
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Okamoto Shingo
Third Department Of Internal Medicine Nara Medical University
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Kojima Hideyuki
Third Department Of Internal Medicine Nara Medical University
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Fujimoto Masao
Third Department Of Internal Medicine Nara Medical University
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Uemura Masahito
Third Department Of Internal Medicine Nara Medical University
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Nakajima Yoshiyuki
First Department Of Surgery Nara Medical University
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Fukui Hiroshi
Third Department Of Internal Medicine Nara Medical University
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Yoshikawa Masahide
Department Of Gastroenterology Ishinkai Yao General Hospital
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Tsuro Kiminori
Third Department of Internal Medicine, Nara Medical University
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Kou Saihou
First Department of Surgery, Nara Medical University
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