Percutaneous CTguided Radiofrequency Ablation of Pulmonary Malignant Tumors:Preliminary Report

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概要

• 論文の詳細を見る

• Objective: Radiofrequency ablation (RFA) is frequently used for hepatic malignant tumors, but few reports discuss its use for lung tumors. We report our pilot clinical study with RFA for the treatment of pulmonary malignant tumors. Patients and Methods: Five patients with histologicallyproven malignant primary and three metastatic lung tumors underwent a total of 11 RFA procedures. RFA was performed in two patients as palliative therapy to shrink the tumors and in six as radical therapy. All RFA was performed by the percutaneous CTguided approach. Results: Three tumors were completely ablated by one procedure. Contrast CT revealed cyst cavity formation or scar formation at these three tumors. Gd contrastenhanced MRI revealed cystic lesions with ringlike enhancement or scar formation. Partial ablation after the first procedure was noted in six tumors including the two palliative cases. RF ablation was well tolerated in all patients. Intraprocedural complications included six cases of pneumothorax (one patient required chest tube placement), six cases of pleural effusion (two patients required chest tube placement), one case of pneumonia (improved immediately with antibiotics), three cases of bloody sputum (mild), and six cases of chest pain (all cases after the procedure). Conclusions: This pilot clinical study demonstrates that CTguided RFA is a relatively safe and effective treatment option for malignant lung tumors. Additional trials are needed to determine the safety, efficacy, and optimal indications of RFA.

• 社団法人 日本内科学会の論文

著者

• Hashimoto Toshio

  Department Of Cardiovascular Medicine Nara Medical University

• Nakamura Hiroyuki

  Fifth Department Of Internal Medicine Tokyo Medical University Kasumigaura Hospital

• Oh-ishi Shuji

  Fifth Department Of Internal Medicine Tokyo Medical University

• KISHI Koji

  Fifth Department of Internal Medicine, Tokyo Medical University

• Kobayashi Katsuyuki

  Fifth Department Of Internal Medicine Tokyo Medical University Kasumigaura Hospital

• Matsuoka Takeshi

  Fifth Department Of Internal Medicine Tokyo Medical University (kasumigaura Hospital)

• MATSUOKA Takeshi

  Fifth Department of Internal Medicine, Tokyo Medical University, Kasumigaura Hospital

• Hatao Hidekazu

  Fifth Department of Internal Medicine, Tokyo Medical University, Kasumigaura Hospital

• Kishi Koji

  Fifth Department of Internal Medicine, Tokyo Medical University, Kasumigaura Hospital

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