Pulmonary Toxicity by a Cytotoxic Agent, S-1
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概要
- 論文の詳細を見る
A 72-year-old man with tongue carcinoma complained of dyspnea on exertion 18 days after starting treatment with S-1. Chest radiograph and CT scan suggested diffuse interstitial lesions with ground glass opacity on both lungs. Bronchoalveolar lavage and transbronchial lung biopsy revealed moderate lymphocyte infiltration with granuloma. Drug lymphocyte stimulation test was positive against tegafur, one of the components of S-1. These findings were consistent with S-1-induced lung injury. Both his symptoms and the radiographic findings were resolved dramatically after high-dose corticosteroid therapy. Clinicians should be aware that S-1 has the potential to cause lung injury when it is included in chemotherapy.
- 社団法人 日本内科学会の論文
著者
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Hiroshima Kenzo
Diagnostic Pathology Graduate School Of Medicine Chiba University
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Kuriyama Takayuki
Respirology, Chiba University
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Tada Yuji
Respirology, Chiba University
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Takiguchi Yuichi
Respirology, Chiba University
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Fujikawa Ayako
Respirology, Chiba University
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Kitamura Atsushi
Respirology, Chiba University
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Kurosu Katsushi
Respirology, Chiba University
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Sakao Seiichiro
Respirology, Chiba University
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Kasahara Yasunori
Respirology, Chiba University
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Tanabe Nobuhiro
Respirology, Chiba University
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Tatsumi Koichiro
Respirology, Chiba University
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Hiroshima Kenzo
Diagnostic Pathology, Chiba University
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