Root resorption and the OPG/RANKL/RANK system: a mini review

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概要

• 論文の詳細を見る

• Odontoclastic root resorption is a significant clinical issue in relation to orthodontic tooth movement, and resorption of the roots of primary teeth is an intriguing biological phenomenon. The functional coordination of the OPG/RANKL/RANK system seems to contribute not only to alveolar remodeling, but also to resorption during orthodontic tooth movement and physiological root resorption. Serum OPG and s-RANKL are related to regulation of bone homeostasis by the OPG/RANKL/RANK system, and determination of their concentrations might be useful for predicting the rate of bone remodeling during orthodontic tooth movement, the net effect between bone remodeling and root resorption, and the degree of root resorption. It is therefore rational to speculate that a study of the levels of OPG and s-RANKL in blood and GCF, in relation to the degree of root resorption during orthodontic tooth movement, using healthy experimental animals and a carefully planned and organized experimental design, may be able to answer this intriguing question. (J. Oral Sci. 50, 367-376, 2008)

• 日本大学歯学部の論文

著者

• Tyrovola Joanna

  Department of Orthodontics, School of Dentistry, University of Athens

• Makou Margarita

  Department of Orthodontics, School of Dentistry, University of Athens

• Perrea Despoina

  Laboratory For Experimental Surgery and Surgical Research 'Christeas Hall', School of Medicine, University of Athens

• Spyropoulos Meropi

  Department of Orthodontics, School of Dentistry, University of Athens

関連論文

• Associations between osteoprotegerin and femoral neck BMD in hemodialysis patients
• Relation of soluble RANKL and osteoprotegerin levels in blood and gingival crevicular fluid to the degree of root resorption after orthodontic tooth movement
• Root resorption and the OPG/RANKL/RANK system: a mini review

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