Susceptibility of Enterococcus faecalis biofilm to antibiotics and calcium hydroxide

スポンサーリンク

概要

• 論文の詳細を見る

• The purpose of this study was to investigate the antimicrobial efficacy of six groups of antibiotics and calcium hydroxide against <I>Enterococcus faecalis</I> biofilm in a membrane filter model. Two-day-old <I>E. faecalis</I> (ATCC 29212) biofilm was exposed to ampicillin, co-trimoxazole, erythr omycin, oxytetracycline, vancomycin, vancomycin followed by gentamicin, Ca(OH)<Sub>2</Sub>, and phosphate-buffered saline (control). After 1 h of exposure, the antimicrobial activity was neutralized by washing each disc five times in PBS, and then the colony-forming units of the remaining viable bacteria on each disc were counted. The results revealed that only erythromycin, oxytetracycline and Ca(OH)<Sub>2</Sub> showed 100% biofilm kill. An ANOVA with a Bonferroni post hoc test (<I>P</I> < 0.05) detected significant differences among the test agents, except in the ampicillin group versus the co-trimoxazole group. It is concluded that erythromycin, oxytetracycline and Ca(OH)<Sub>2</Sub> are 100% effective in eliminating <I>E. faecalis</I> biofilm, whereas ampicillin, co-trimoxazole, vancomycin, and vancomycin followed by gentamicin are ineffective. (J. Oral Sci. 49, 161-166, 2007)

著者

• Chai Wen

  Department Of Chemistry Rikkyo(st.paul's) University

• Sallam Atiya

  Department of Preventive and Social Medicine, Faculty of Medicine, University of Malaya

• Hamimah Hassan

  Department of Medical Microbiology, Faculty of Medicine, University of Malaya

• Cheng Soo

  Department of Medical Microbiology, Faculty of Medicine, University of Malaya

• Abdullah Mariam

  Department of Conservative Dentistry, Faculty of Dentistry, University of Malaya

• Chai Wen

  Department of General Dental Practice and Oral and Maxillofacial Imaging, Faculty of Dentistry, University of Malaya

関連論文

• Biodegradation of Bisphenol A by Cultured Cells of Caragana chamlagu(Organic Chemistry)
• Biotransformation of Cycloalkanediones by Caragana chamlagu
• Susceptibility of Enterococcus faecalis biofilm to antibiotics and calcium hydroxide

スポンサーリンク