Transmission, diversity and virulence factors of Streptococcus mutans genotypes

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概要

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• Dental caries is an infectious and transmissible disease, in which many genetic, environmental and behavioral risk factors interact. The mutans streptococci (MS), mainly <I>Streptococcus mutans</I> and <I>Streptococcus sobrinus</I> are the microorganisms most strongly associated with this disease. The main virulence factors associated with MS cariogenicity include adhesion, acidogenicity and acid tolerance. These properties work together to modify the physico-chemical properties of the biofilm, resulting in ecological changes in the form of increased proportions of S. <I>mutans</I> and other acidogenic and aciduric species. In addition, reports of higher numbers of S. <I>mutans</I> genotypes with increased virulence in caries-active subjects suggest the importance of microenvironmental factors in increasing the risk of caries. This review focuses on the transmission and establishment of different genotypes of <I>S. mutans</I> and the role they play in the development of dental caries. (J. Oral Sci. 47, 59-64, 2005)

• 日本大学歯学部の論文

著者

• Höfling José

  Department of Oral Diagnosis, Microbiology and Immunology, Piracicaba Dental School, University of C

• Gonçalves Reginaldo

  Department of Oral Diagnosis, Microbiology and Immunology, Piracicaba Dental School, University of C

• Napimoga Marcelo

  Department of Oral Diagnostics, Faculty of Dentistry of Piracicaba, University of Campinas

• Klein Marlise

  Department of Oral Diagnostics, Faculty of Dentistry of Piracicaba, University of Campinas

• Kamiya Regianne

  Department of Oral Diagnostics, Faculty of Dentistry of Piracicaba, University of Campinas

関連論文

• Candida spp. in periodontal disease: a brief review
• Transmission, diversity and virulence factors of Streptococcus mutans genotypes

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