Use of Recombinant Activated Factor VII in Cardiac Surgery for an Effective Treatment of Severe Intractable Bleeding
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概要
- 論文の詳細を見る
Experience gained with administration of supranormal-therapeutic doses (90 μg/kg) of recombinant activated factor VII in 7 cardiac surgery patients is presented. The patients were given recombinant activated factor VII postoperatively for intractable bleeding, 5 of them after surgical revision. Administration of recombinant activated factor VII was associated with significant reduction in blood loss (P < 0.05) and shortening of INR and aPTT in laboratory tests. None of the patients needed reoperation. Administration of recombinant activated factor VII proved highly effective in management of massive hemorrhage in cardiac surgery.
- International Heart Journal刊行会の論文
著者
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Vanek Tomas
Department of Cardiac Surgery, 3rd Medical School of Charles University, and Kralovske Vinohrady University Hospital
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Jares Martin
Department of Cardiac Surgery, 3rd Medical School of Charles University, and Kralovske Vinohrady University Hospital
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Straka Zbynek
Department of Cardiac Surgery, 3rd Medical School of Charles University, and Kralovske Vinohrady University Hospital
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Votava Jan
Department of Cardiac Surgery, 3rd Medical School of Charles University, and Kralovske Vinohrady University Hospital
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Brucek Peter
Department of Cardiac Surgery, 3rd Medical School of Charles University, and Kralovske Vinohrady University Hospital
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Hrabak Jakub
Department of Cardiac Surgery, 3rd Medical School of Charles University, and Kralovske Vinohrady University Hospital
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- Use of Recombinant Activated Factor VII in Cardiac Surgery for an Effective Treatment of Severe Intractable Bleeding