Identification of Additional Quantitative Trait Loci (QTL) Responsible for Susceptibility to Infectious Pancreatic Necrosis Virus in Rainbow Trout
スポンサーリンク
概要
- 論文の詳細を見る
Previous typing of microsatellite markers in a BC1F1 backcross rainbow trout Oncorhynchus mykiss revealed two quantitative trait loci (QTL) with a significant impact on susceptibility to infectious pancreatic necrosis. In the present study, additional genetic markers were mapped using the same strain in order to increase QTL resolution. A total of 199 individuals were screened at 226 marker loci (106 microsatellites, 116 amplified fragment length polymorphism markers, classical major histocompatibility complex molecules [MHC class I, nonclassical MHC class I, MHC class II] and tyrosinase) and the QTL were determined by single-point and interval mappings. Seven QTL were distinguished in the linkage groups RT-11, 12, 17, 23, 26, 29 and 31, in addition to the two already known in RT-3 and 22. The major QTL were those in RT-3, 12 and 22; whereas the classical MHC class I locus Onmy-UBA and the MHC class II locus Onmy-DAB were not associated with any of the QTL, a nonclassical MHC class I region with Onmy-UCA, Onmy-UDA, and Onmy-UEA mapped to the major QTL on RT-3.
著者
-
KHOO Sok-Kean
Faculty of Marine Science, Tokyo University of Marine Science and Technology
-
Dijkstra Johannes
Tamaki Station National Research Institute Of Aquaculture Fisheries Research Agency
-
Yoshiura Yasutoshi
Tamaki Station, National Research Institute of Aquaculture, Fisheries Research Agency
-
Ozaki Akiyuki
National Research Institute of Aquaculture, Fisheries Research Agency
-
Ototake Mitsuru
Tamaki Station, National Research Institute of Aquaculture, Fisheries Research Agency
-
Sakamoto Takashi
Faculty of Marine Science, Tokyo University of Marine Science and Technology
-
Okamoto Nobuaki
Faculty of Marine Science, Tokyo University of Marine Science and Technology
関連論文
- IPN抗病性に関連する新規ニジマス遺伝子マーカー
- Identification of Additional Quantitative Trait Loci (QTL) Responsible for Susceptibility to Infectious Pancreatic Necrosis Virus in Rainbow Trout