Cobalt(II) salt-quinoline compound interaction: Combined mutagenic activity in Salmonella typhimurium and strength of coordinate bond in the mixtures.

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概要

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• The mutagenic activity of cobalt (II) chloride (CoCl2) was examined using the Salmonella test system in the presence of quinoline compounds. CoCl2, which itself is non-mutagenic, exhibited mutagenicity when combined with quinoline, 2-methylquinoline, 3-methylquinoline, 4-methylquinoline, 6-methylquinoline, 7-methylquinoline, 2-aminoquinoline, 4-aminoquinoline and 8- aminoquinoline in strains TA1537 and TA2637. Mixtures of CoCl2 and 8- methylquinoline, 3-aminoquinoline or 5-aminoquinoline did not induce mutations. The combined mutagenicity may be due to a formation of complexes between the Co(II) cation and quinoline compounds judging from the spectral data.

• 日本遺伝学会の論文

著者

• TSURUTA Satoshi

  Environmental Technology Service Co., Ltd.

• LIU Song-Yuan

  Faculty of Engineering, Kyushu Institute of Technology

• KATO Yasuhiko

  Faculty of Engineering, Kyushu Institute of Technology

• OGAWA H.

  Faculty of Engineering, Kyushu Institute of Technology

• SAKATA Kazunori

  Faculty of Engineering, Kyushu Institute of Technology

• MINO Haruhiko

  Faculty of Engineering, Kyushu Institute of Technology

関連論文

• Interaction of DNA and Cobalt(II) Chloride in the Presence of Heteroaromatic Compounds
• Cobalt(II) salt-quinoline compound interaction: Combined mutagenic activity in Salmonella typhimurium and strength of coordinate bond in the mixtures.
• Mutagenicity of metal salt in combination with 9-amino-acridine in Salmonella typhimurium.

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