Chromosomal aberrations induced by hydrogen peroxide in cultured mammalian cells.

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概要

• 論文の詳細を見る

• Chromosomal aberrations were observed in cultured mammalian cells (CHO-K1 Chinese hamster cells, V79 Chinese hamster cells, Syrian hamster cells, and BALB/c mouse cells) after treatment with hydrogen peroxide (H2O2; 0.1-0.5mM or 0.01-0.1mM) for 3h. The cytotoxic and clastogenic effects of H2O2 were clearly reduced by the addition of catalase. In contrast to the clastogenic potential, H2O2 did not enhance the frequency of mutation in V79 cells, whether the marker for mutation was 8-azaguanine resistance or ouabain resistance.

• 日本遺伝学会の論文

著者

• TSUDA HIROHISA

  Biological Research Center, Central Research Institute, The Japan Tobacco and Salt Public Corporation

関連論文

• 培養チャイニ-ズハムスタ-細胞における MNNG 誘発突然変異の頻度に及ぼすカフェイン効果の時間依存性〔英文〕
• Chromosomal aberrations induced by hydrogen peroxide in cultured mammalian cells.

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