ニワトリにおける移植組織対宿主反応の遺伝子支配〔英文〕
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A study has been made to determine whether the blood group gene B controls the focus formation on chorioallantoic membrane as well as splenomegaly, and if it is a case, to determine on the effect of the gene B quantitatively.It was found that the gene B controlled the focus formation as well as splenomegaly when the host embryos possessed the antigen controlled by the gene B. In the absence of B antigen, other antigens were responsible to produce foci without changes in spleen weight. It suggested that a second gene-C blood group gene-controlled the focus formation without splenomegaly when the host embryos possessed no antigen controlled by the gene B.In BABA hosts, BbBb donor produced the largest focus number than did BBBB, BMBM, BGBG, and BKBK donors. Both BBBB and BMBM donors produced intermediate focus numbers. It is suggested that the differences in the competence of donor to produce focus may depend upon the differences in genotypes of the gene B in the donors.
- 日本遺伝学会の論文
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