The Yeast Checkpoint Kinase Dun1 Downregulates DIN7 in the Absence of DNA Damage

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概要

• 論文の詳細を見る

• Yeast DIN7 is a DNA damage-inducible gene. Its expression is increased in the absence of Dun1, a DNA damage checkpoint kinase. We identified a DIN7 promoter region responsible for Dun1-mediated downregulation and found that DIN7 expression was not further increased in response to hydroxyurea in Δdun1 cells. Thus DIN7 repression by Dun1 can be released upon DNA damage.

• 社団法人 日本農芸化学会の論文

著者

• YOSHIDA Minoru

  Chemical Genetics Laboratory, RIKEN

• YOSHITANI Ayako

  Chemical Genetics Laboratory, RIKEN Discovery Research Institute

• LING Feng

  Chemical Genetics Laboratory, RIKEN Discovery Research Institute

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