Association between Alkaline Phosphatase and Anemia in Rural Japanese Men: The Nagasaki Islands study
スポンサーリンク
概要
- 論文の詳細を見る
Although bone metabolism is reportedly associated with production and maturation of blood corpuscles, and serum alkaline phosphatase (ALP) levels have been associated with bone metabolism, no published study has investigated the association between ALP and anemia. Furthermore, although ALP is known as an enzyme affected by alcohol consumption, there are no reports in the literature on associations between ALP and the risk of anemia in relation to drinking status. We conducted a cross-sectional study of 907 men aged 30-89 years undergoing a general health check-up to investigate the associations between ALP and anemia in relation to drinking status. Of the 907 participants, 120 men were diagnosed with anemia. The association between ALP and anemia was J-shaped. With the second quartile of ALP (194-228 IU/L) (Q2) as the reference group, the multivariable adjusted OR and 95%CI for anemia were 1.91 (95%CI: 0.96-3.82) for <194 IU/L (Q1), 1.84 (95%CI:0.93-3.62) for 229-277 IU/L (Q3) and 2.83 (95%CI:1.49-5.37) for >277 IU/L (Q4). When the analysis was limited to non-drinkers, the associations became stronger with corresponding values of 3.34 (95%CI: 1.28-8.74), 3.18 (95%CI: 1.28-7.88) and 3.22 (95%CI:1.37-7.59). Not only lower but also higher levels of serum ALP are associated with anemia for men, especially non-drinkers. For analyses of associations between ALP and anemia, alcohol consumption should thus be considered a potential confounder.
- Nagasaki University School of Medicineの論文
Nagasaki University School of Medicine | 論文
- Studies on Histological Grading of Malignancy of Carcinoma of The Uterine Cervix
- A. femoralis and its Branches in Macacus cyclopsis
- Spray Method, A New Technique for Investigation of Vessels on the Tissue Surface.
- Leukocyte Alkaline Phosphatase in Hematological Disorders
- Studies on the Cerebral Arteries of Macacus cyclopsis