体外式汎用心臓ペースメーカの研究

概要

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A microcomputer-based pacemaker system for evaluating the pacemaker treatment of arrhythmia is described. This system can function not only as a demand pacemaker but also as a pacemaker for tachycardia control as well as a defibrillator. All stimulations are delivered through a catheter electrode in the right ventricle and a subcutaneous electrode. For the detection of arrhythmia, ECG and blood pressure signals are used. In particular, the blood pressure signal is useful to detect the actual heart rate during burst pulse pacing which is capable of controlling ventricular tachycardia automatically. Moreover, during burst pulse pacing, special attention is paid to detecting hypotension in order not to cause ventricular fibrillation. Pacing failure is quickly sensed from variations in R-wave pulse amplitude and pulse width. When, after the heart has been stimulated, the ECG shows no response, and hypotension continues without any rhythmic contraction, a battery-operated defibrillator is triggered and defibrillation is accomplished automatically. This system has been designed using two 16Fbit microcomputers, one of which performs signal processing aria the other, output control. In animal experiments, examples of the use of the system for demand pacing, tachycardia termination, and defibrillation are given. This system may be used to study tachycardia termination and defibrillation in clinical laboratories.
日本生体医工学会の論文