Protecting-Group-Free Route to Hydroxylated Pyrrolidine and Piperidine Derivatives through Cu(I)-Catalyzed Intramolecular Hydroamination of Alkenes

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概要

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• An efficient approach to hydroxylated pyrrolidine and piperidine derivatives through the intramolecular hydroamination catalyzed by a Cu(I)-Xantphos system is described. The transformation allows for the short synthesis of N-alkylated azasugars without a protection/deprotection event of the hydroxy groups.

• Georg Thieme Verlagの論文

著者

• SAWAMURA Masaya

  Department of Chemistry, Faculty of Science, Hokkaido University

• Yoshida Mika

  Department Of Chemistry Faculty Of Science Hokkaido University

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• Protecting-Group-Free Route to Hydroxylated Pyrrolidine and Piperidine Derivatives through Cu(I)-Catalyzed Intramolecular Hydroamination of Alkenes

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