New Diketopiperazine Derivatives Isolated from Sea Urchin-Derived Bacillus sp.
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概要
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Two new diketopiperazine derivatives, bacillusamides A (1) and B (2), have been isolated from the EtOAc extract of the sea urchin-derived Bacillus sp. along with the known cyclo(-L-pro-L-val-) (3), cyclo(-L-pro-L-tyr-) (4), cyclo(-L-pro-L-phe-) (5). These structures were elucidated by extensive spectroscopic methods. Furthermore, the absolute configurations of the amino acid residues were determined using Marfey's method. Compound 1 displayed weak antifungal activity against Aspergillus niger.
- The Pharmaceutical Society of Japanの論文
- 2011-01-00
The Pharmaceutical Society of Japan | 論文
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