Oncogenes in Tumors of Gallbladder and Biliary Tract

概要

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Progress in molecular biology has clarified the involvement of several genetic alterations of proto-oncogenes and tumor suppressor genes in carcinogenesis and cancer progression. Currently, some very sensitive methods suited for the analysis of mutational events in cancer are being successfully employed. Here we give an outline of the well-established mutations of K-ras, p53, and p16 in gallbladder and bile duct carcinomas, which occur in high incidence.
2004-02-25