経口抗凝固薬（ワルファリン）内服患者の抜歯に関する検討

概要

論文の詳細を見る
We retrospectively reviewed and discussed hematostatic managements for tooth extraction in patients　maintained on oral anticoagulant. From 2001 to 2007, 109 patients maintained with oral anticoagulant treatment　underwent a total of 143 occasions of tooth extraction in our department.At the time of tooth extraction, oral anticoaglant medication was maintained on 76 occasions (53%), and had been discontinued on 55　occasions (38%). Postoperative bleeding happened in 5 cases (9.1%) in patients without interruption of oral　anticoagulant, and in 3 cases (3.9 %) in patients with interruption. There was no significant difference in the　Prothrombin Time International Normalized Ratio (PT-INR) and in postoperative hemostatic procedures between them.The results of this study suggest that dental extraction can be performed without modification　of oral anticoagulant treatment in cases where the PT-INR is less than 3.0.Strict local hemostatic procedures　are necessary to prevent postoperative bleeding
2010-12-10