カネミ油症検診者に見られる血清クレアチンキナーゼとアルドラーゼの異常
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特集号 油症とPCB及び関連化合物研究報告 第19集 責任編集者 古江増隆 / The Nineteenth Reports of the Study on Yusho and PCBs and Related Compounds Guest Editor Masutaka FurueWe studied the rates of the patient with the elevation of serum creatine kinase using the routine medical checkup data from KANEMI YUSHOU patients between 1995 and 2001. We also studied the serum aldolase level and light microscopic observation of muscle tissue in rats during strenuous exercise given the polychlolinated biphenyls. Fifteen percent of the patients showed the elevation of serum creatine kinase. The patients with the elevation of serum creatine kinase also showed a higher concentration of polychlolinated biphenyls in their blood. 47.7% of the patients show low aldolase. There is no interrelation between the ldolaselevels and PCBs or PCQs. There is also no interrelation between the serum levels ofaldolase and creatine kinase. The rats given polycholorinated biphenyls showed a slightincrease of necrotic fibers during strenuous exercise. Polycholorinated biphenyls may playsome role for muscle necrosis. We could not clarify the significance of low serum aldolase in KANEMI YUSHOU.
- 福岡医学会,Fukuoka Medical Associationの論文
- 2003-05-25
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