Improvement of constipation and liver function by plant-derived lactic acid bacteria : A double-blind, randomized trial
スポンサーリンク
概要
- 論文の詳細を見る
Objective: Lactic acid bacteria (LAB) contribute to human health; however, the probiotic properties vary among strains classified into the same species. The primary objective of this study was to evaluate the effects of yogurts made by different types of LAB on the gastrointestinal system. The yogurts are also evaluated by measuring serum lipid contents and liver functional indicators as secondary objective.Methods: Healthy human adults (n=68) with some complaints with regard to intestinal health, including constipation and diarrhea, were randomly assigned to receive one of three types of yogurt in a double-blind manner: (type A) yogurt made by plant-derived LAB (mainly Lactobacillus (Lb.) plantarum SN35N); (type B) yogurt made by plant-derived LAB (mainly Lb. plantarum SN13T); (type C) yogurt made by animal-derived LAB (mainly Lactococcus lactis A6 and Streptococcus thermophilus 510) as a control. The subjects consumed 100g of yogurt daily for 6 weeks. Data were collected from clinical visits at 2-week intervals and by diaries used to record defecation and health conditions.Results: Drastic and constant increments of defecation frequency in subjects with constipation were observed with type A and B yogurts but not with type C yogurt. Type B and C yogurts resulted in decreases in total and LDL cholesterol. The serum concentrations of liver functional parameters were improved by the type B yogurt (12-25% reduction).Conclusions: The present study suggests that Lb. plantarum SN13T exhibits a superior probiotic effect on constipation in addition to improving the serum lipid contents and liver function.
著者
関連論文
- 2Da08 D-サイクロセリン生合成に関与するセリンO-アセチルトランスフェラーゼの構造解析(酵素学・酵素工学,一般講演)
- 2Ma06 変異導入による薔薇の香気成分を産生する植物乳酸菌の分子育種(食品科学・食品工学,一般講演)
- 1Bp21 クラスIIbバクテリオシンbrevicin 174Aの産生制御の分子機構解明(遺伝子工学,一般講演)
- 2E09-1 Lactobacillus brevis 925Aにおけるバクテリオシン産生とプラスミドの関係(遺伝子工学・核酸工学,一般講演)
- 2H10-3 Streptomyces lavendulae ATCC11924が保有する二次代謝遺伝子クラスターの機能と遺伝子発現制御機構の解析(遺伝子工学,核酸工学,一般講演)
- 1G09-4 酒粕に含まれるチロシナーゼ阻害剤と酵素阻害の速度論的解析(酵素学,酵素工学,タンパク質工学,一般講演)
- 2A15-5 D-Cycloserine生産菌の自己耐性機構 : Alanine racemaseの構造生物学的解析(酵素学・酵素工学・タンパク質工学,一般講演)
- Improvement of constipation and liver function by plant-derived lactic acid bacteria : A double-blind, randomized trial
- (244) ホウレンソウ萎凋病を抑制する乳酸菌Pediococcus pentosaceus KMC05株の免疫賦活作用と植物体における定着性(平成18年度日本植物病理学会大会講演要旨)
- 植物乳酸菌のヘルスサイエンス
- 磁気センサ型指タッピング装置の再現性評価
- 2P-222 ロイシルブラストサイジンSを脱アミノアシル化する酵素の同定(生合成,天然物化学,一般講演)
- 1P-015 D-サイクロセリンの生合成においてN^ω-ヒドロキシ-L-アルギニンの生成に関与するdcsA遺伝子の解析(遺伝子工学,一般講演)
- 1P-069 O-ウレイド-L-セリン合成酵素DcsDの活性発現に重要なアミノ酸残基の特定(酵素学,酵素工学,一般講演)