Thickness of photoreceptor layers in polypoidal choroidal vasculopathy and central serous chorioretinopathy.
スポンサーリンク
概要
- 論文の詳細を見る
BACKGROUND: To evaluate retinal thickness using spectral-domain optical coherence tomography (SD-OCT) with reduced speckle noise in eyes with polypoidal choroidal vasculopathy (PCV) compared to those with normal eyes and those with central serous chorioretinopathy (CSC). METHODS: We retrospectively reviewed cases of foveal serous retinal detachment in 36 eyes of 36 patients with active CSC and 23 eyes of 23 patients with active PCV, and 44 eyes of 44 normal subjects. Patients were examined using SD-OCT with reduced speckle noise, and the thickness of the outer nuclear layer (ONL), photoreceptor inner segment (IS), and photoreceptor outer segment (OS) were measured. RESULTS: The ONL and IS were thicker in normal eyes than in eyes with CSC or PCV (P < 0.001). The OS was significantly less thick in eyes with PCV than in normal eyes (P < 0.001), whereas there was no significant difference between eyes with CSC and normal eyes. The thickness of IS and OS in eyes with PCV was related to fibrin or hemorrhage being present in the subretinal space. In eyes with PCV, best-corrected visual acuity at baseline correlated with IS thickness (P = 0.023). CONCLUSIONS: Thinning of each photoreceptor layer was observed in the eyes of PCV patients as compared to that observed in the case of normal individuals. The differentiating factors between PCV and CSC, observed using SD-OCT, include the thinning of the OS in eyes with PCV, which makes SD-OCT helpful in differentiating PCV from CSC. More severe photoreceptor alterations were seen in PCV, because fibrin and hemorrhage were present in the subretinal space, which correlated with poorer vision.
論文 | ランダム
- Oxygen self-diffusion in cerium oxide doped with Nd (学外発表論文) -- (第1プロジェクト〔環境安全における超微量計測技術の研究開発〕関係)
- Preparation of Flat Calcite(10 1 4) Surface by Thermal Treatment Method (学外発表論文) -- (第1プロジェクト〔環境安全における超微量計測技術の研究開発〕関係)
- Study on Grain Boundary Grooving by Surface Diffusion in Bicrystal Ceramics Using Atomic Force Microscopy (学外発表論文) -- (第1プロジェクト〔環境安全における超微量計測技術の研究開発〕関係)
- Atomic Force Microscopy Study of Surface Diffusion in Polycrystalline CeO2 via Grain Boundary Grooving (学外発表論文) -- (第1プロジェクト〔環境安全における超微量計測技術の研究開発〕関係)
- Intrinsic and Extrinsic Oxygen Diffusion and Surface Exchange Reaction in Cerium Oxide (学外発表論文) -- (第1プロジェクト〔環境安全における超微量計測技術の研究開発〕関係)