二重盲検法による尿路結石症の疼痛発作に対する経口ペンタゾシンの有効性について

概要

論文の詳細を見る
Comparative analysis of spasmolytic and analgesic effect of pentazocine 25 mg given orally (PAT) and 15 mg given parenterally (PAI) was performed on a basis of double blind trial in 98 patients who had an acute attack of urinary stone colic. Analgesic effect of PAT become apparent less quickly than PAI; in most cases analgesia was attained after 30 minutes following the administration of PAT. However, PAT was equally effective to PAI if observed for 60 minutes. The side effects were less frequent and minimal in PAT. It was concluded that orally administered pentazocine 25 mg was equally effective to parenteral pentazocine IS mg in the treatment of urinary stone colic.