最近の泌尿器科領域における感染症および術創感染予防対策について

概要

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1. Four to 30 grams of SB-PC were given daily to 10 patients for treatment of urinary tract infections and to 4 patients for post-operative wound infections for 6 to 16 days. Ten grams of SB-PC and 4 grams of cephalothin (CET) were simultaneously given to 12 patients for prophylaxis of post-operative wound infections for 7 to 16 days. 2. Bacteria such as Pseudomonas from 8 patients, E. coli from 2 patients, Klebsiella from 2 patients and Enterobacter from 1 patient were isolated from 13 patients out of 14 patients treated with SB-PC alone. Good results were obtained in 8 cases due to Pseudomonas, in 1 case due to E. coli and in 1 case due to Klebsiella but a negative result was obtained in 1 case due to Enterobacter. 3. In the patients for prophylaxis of post-operative wound infections, good results were obtained in 1 case out of 4 treated with SB-PC alone and in 11 cases out of 12 treated with SB-PC+CET. 4. No side effects were observed. When biochemical analysis (Ht value, BUN, GOT and GPT) and electrolyte analysis (Na, K and CI in blood serum) were carried out before and during the administration of this drug, the distinct difference of these values was not observed.
泌尿器科紀要刊行会の論文