Klinefelter症候群にかんする臨床的研究-1-Klinefelter症候群におけるLH-RH試験
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概要
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100µg of synthetic LH-RH was intravenously administered to seven cases of Klinefelter's syndrome with karyotype of 47, XXY and the plasma LH and FSH were determined to know their pituitary response. The following results were obtained. 1. The maximum response level of plasma LH (134.2±89.4 mIU/ml) was observed at 20 minutes. The maximum net increase and factorial increase were 96.5±79.9mIU/ml and 4.0± 2.6 respectively. The LH level remained significantly higher even at 60 minutes. 2. The plasma FSH showed increase of 1.2 to 1.4 times of the pretest level, the maximum net increase being 58.0±21.6 mIU/ml. There was however, no significant difference between them. The pituitary gonadotropin-producing cells of Klinefelter's syndrome were capable to response to synthetic LH-RH and possessed reserved ability to excrete excessive amount of LH and FSH.
- 泌尿器科紀要刊行会の論文
泌尿器科紀要刊行会 | 論文
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