泌尿器科領域におけるS-804の使用経験

概要

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Twenty-four patients with urological diseases who had had intractable complaints with no organic change observed in the urological organs and whose complaints had been considered due to neurogenic factors, were administered with S-804, a new minor tranquilizer of the benzodiazepine system. The administration was 30 mg daily, in 3 divided doses. The effectiveness of the drug was classified into excellent, good, and poor. S-804 was found excellent in 10 (41.7%) of 24 cases, good in 11 (45.8%), and poor in 3 (12.5%). The effectiveness was thus 87.5 %. The drug was effective in all of 7 cases of nervous pollakisuria, all of 4 cases of sequela of cystitis, and all of 6 cases of urethral neurosis. As for side effect, 3 cases complained of drowsiness, and from one of them the drug had to be withdrawn. In the remaining 2 cases, the side effect was mild. No change was noted in the blood picture, liver functional tests, etc. The above findings indicate that S-804 is a minor tranquilizer not less effective than even diazepam.
泌尿器科紀要刊行会の論文