[原著］小児期特発性血小板減少性紫斑病の臨床像と治療

概要

論文の詳細を見る
Twenty six children with idiopathic thrombocytopenic purpura(ITP) were reviewed. These patients were classified into three types ; 13 patients of acute type, 10 patients chronic type, and 2 patients of recurrent type. One patient could not be classified because of short observation period. Compared with chronic ITP, children with acute ITP were younger, and more frequently affected with preceding infections. The most common symptom in acute ITP was subcutaneous hemorrhage. None had intracranial hemorrhage. There was no appreciable difference between the groups with or without steroid administration, when the change in the mean platelet numbers was evaluated. High-dose gammaglobulin therapy should be indicated only for serious younger patients who can not keep rest. In chronic ITP, any therapies had only transient effects except splenectomy. Two patients with splenectomy maintained completeresponse without severe infections. It was suggested that splenectomy should be recommended for refractory chronic ITP.
琉球医学会,Ryukyu Medical Associationの論文