[症例報告]潰瘍性大腸炎におけるメトロニダゾールの使用経験

概要

論文の詳細を見る
Sulfasalazine and corticosteroids have been used for the treatment of ulcerative colitis. Recently, it is investigated to use metronidazole for treatment of ulcerative colitis. We tried to use metronidazole for three patients with ulcerative colitis , to whom neither sulfasalazine nor corticosteroids were effective. In case 1 the patient was 37-year-old female,to whom conticosteroids had been ineffective. After treatment by metronidazole together with corticosteroids, the symptoms were improved. In case 2 the patient was 74-year-old female, who had relapsed during treatment with sulfasalazine. Treatment with metronidazole alone resulted in the remission of disease. In case 3 the patient was 32-yearold female, to whom the treatment with sulfasalazine and corticosteroids enema had been ineffecitve. By use of metronidazole together with sulfasalazine, she had remission. It seems that metronidazole is useful for the treatment of ulcerative colitis, especially in patients who did not respond to other drugs.
琉球大学医学部,Faculty of Medicine, University of the Ryukyusの論文