原因不明の腎性血尿と血清亜鉛に関する臨床的研究

概要

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1) 165例の腎性血尿を有する症例の血清Zn値を調べた.有意にその血清Zn値は低値を示した.2)血尿の程度が強くなるにつれて,血清Zn値は低下することがわかった.3)血清Zn値は本症の病状の進行の程度を示すものと考えられる.4)本症で継続的に長期にわたり血清Zn値が低値を示す症例は腎生検をすべきである.5)本症では血清Zn値は治療効果を検討するひとつのmarkerとしても使用できるThe relationship between red blood cell counts in urine of 165 patients with unknown etiology of renal hematuria and serum zinc levels was examined. There was a significant negative correlation between red blood counts in urine and serum zinc levels. The clinical course and changes of serum zinc levels of 2 cases (case 1: 21 years old female, case 2: 46 years old male) with unknown etiology of renal hematuria are reported. Serum zinc levels showed the clinical stage of unknown etiology of renal hematuria. Renal biopsy should be done in patients with low serum zinc levels and renal hematuria continuing for a long time. Clinically, serum zinc level could be used as a marker of effect of treatment for unknown etiology of renal hematuria. Serum zinc levels were low in 165 patients with renal hematuria.