筋伸張による神経筋伝達の促通効果に及ぼす脚延長の影響　2. Miniature End-Plate Potential 並びに End-Plate Potential について

概要

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In order to clarify the effect of leg-lengthening on neuromuscular facilitation by muscle stretch, using frogs, we examined electrical responses, especially M. E. E. P. s and E. P. P. s in a lengthened legpreparation (lengthened preparation) as well as in a healthy leg preparation (healthy preparation). The following results were obtained. 1. With respect to the frequency of M. E. P. P. s and quantal content, neuromuscular facilitation by muscle stretch decreased apparently in the lengthened preparations with 15% lengthening. 2. There was no significant difference between the amplitude of the M.E. P. P. s of the lengthened preparation and those of healthy preparation. On the basis of the above results, the transmitter release from the presynaptic side in the neuromuscular junction was proved to decrease. On the other hand, it was expected that there would be little change in the postsynaptic side. Thus, it became apparent that decrease in the transmitter release from the presynaptic side was one of the causes of muscle weakness produced by leg-lengthening.
札幌医科大学の論文
1981-12-01