ディスポ-ザブル型拍動流血液ポンプの実験的ならびに臨床的検討

概要

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Pulsatile blood pump (Model PP-11, Nikkiso Co. Ltd.) was studied experimentally, and then, used in 30 open heart surgeries for children less than 20 kg of body weight. At 100 m?/kg/min. of pump output, arterial pressure was maintained 100 ± 11.3 mmHg in systolic and 40 ± 12.5 mmHg in diastolic. Hemolysis was smaller in perfusion with pulsatile than roller pump at 60 minutes of extracorporeal circulation (p<0.01). Bleeding volume from the weaning of cardiopulmonary bypass to the end of surgery was smaller in perfusion with pulsatile than roller pump. There was no difference between both pumps in urinary during and after surgery. Overload of water to the body during extracorporeal circulation was mostly excreted for the first 3 hours after surgery. The difference of core temperature between abdominal wall and sole decreased within 1℃ in both pumps by 3 hours after surgery, but it's difference was smaller in the cases of pulsatile than roller pump during and immediatly after surgery. It is the problem awaiting solution that competition between the heart and the pump appeares at the weaning of extracorporeal circulation.
札幌医科大学の論文