気管支喘息の肺機能 ―FEV1.0％と Slow space/FRC による分類から―
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概要
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Numerous reports are available on the pulmonary function in the presence of attacks of bronchial asthma. Because of its diversified etiologies and pathological factors and also because of its reversibility, conclusions are still to be elucidated. The authors therefore have classified the grades of severity of the disease by the intensity of stridor and dyspnea, and related these symptoms with the pulmonary function indices, namely %VC, FEV1.0%, FRC/TLC, RV/TLC, Slow space/FRC (SS/FRC) and DLCO（LCO下）. It was revealed that none of these indices, when used individually, were satisfactory, but the main objective was achieved by the combined use of tow i.e., FEV1.0% and SS/FRC. This indicates that the progression of the attacks leading to emphysema is of clinical importance in this disease. Therefore, an attempt was made to classify the ventilation function in bronchial asthma by FEV1.0% and SS/FRC : Type A: FEV1.0%, not less than 55%, and SS/FRC, not more than 50% Type B : FEV1.0%, not more than 55%, and SS/FRC, not more than 50% Type C: FEV1.0%, not more than 55%, and SS/FRC, not less than 55% This classification was tentatively named F-S classification. In this classification, types A, B and C denote the grades of severty in the increasing sequence of significance. Miscellaneous other pulmonary function tests were carried out simultaneously with this F-S classifi cation as a basis to study the pulmonary function under attacks of bronchial asthma. As a result, the following patterns were noted. Namely with decreased FEV1.0% and extremely elevated SS/FRC in the progrssion of the attacks leading to emphysema as the basis: 1. Parameters correlated with the F-S classification FRC/TLC, RV/TLC, Pao2, Sao2, Paco2, VD/Vt, A-aDo2 and pulmonary blood perfusion distribution. 2. Parameters correlated partially with F-S classification %VC and pH. 3. Parameters not correlated with F-S classification DLCO, AAO2 and VA. These finding proved the F-S classification to be reasonably applicable.
- 札幌医科大学の論文
- 1978-08-01
札幌医科大学 | 論文
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