遠隔リンパ節転移を伴う十二指腸乳頭部・早期直腸同時性重複癌に対して抗癌剤感受性試験に基づいた化学療法が奏効した1例

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A 52-year-old woman with obstructive jaundice was diagnosed as advanced duodenal cancer with distant lymphnode metastasis and early rectal cancer based on computed tomography (CT) and gastrointestinal series.　Weperformed pancreaticoduodenectomy with D3 lymph node dissection.　Metastatic lymph node tissue was submitted tochemosensitivity test.　Based on the chemosensitivity test, FOLFOX (Leucovorin + 5-FU + Oxaliplatin) was administeredintravenously.　The patient received 3 cycles of FOLFOX chemotherapy until appearance of grade 4 leucopenia and grade3 vomiting.　After the FOLFOX, she received 12 cycles of TS-1 + CDDP chemotherapy without serious complications.　She remained well without any symptoms and pursued normal activity for 27 months. Chemosensitivity test-guidedchemotherapy seems to be an effective regimen as an individualized chemotherapy for advanced duodenal cancer.