Total synthesis of zaragozic acid C by an aldol-based strategy
スポンサーリンク
概要
- 論文の詳細を見る
A total synthesis of zaragozic acid C by a convergent strategy is described in which the key features include (1) the simultaneous creation of the C4 and C5 quaternary stereogenic centers by a Sn(OTf)2-promoted aldol coupling reaction between an α-keto ester and a silyl ketene thioacetal derived from L- and D-tartaric acids, respectively, (2) the direct introduction of lithium acetylide as the C1 side chain equivalent onto the fully functionalized aldehyde, and (3) construction of the bicyclic core structure by acid-catalyzed internal ketalization under kinetically controlled conditions.
- Elsevierの論文
- 2005-11-21
Elsevier | 論文
- Design and operation of an air-conditioning system fueled by wood pellets
- A comparative study of Al and LiF:Al interfaces with poly (3-hexylthiophene) using bias dependent photoluminescence technique
- Evidence of photoluminescence quenching in poly(3-hexylthiophene-2,5-diyl) due to injected charge carriers
- Volume shrinkage dependence of ferromagnetic moment in lanthanide ferromagnets gadolinium, terbium, dysprosium, and holmium
- In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression