フィラリア性乳び尿症における臨床免疫学的研究 : 特に細胞性免疫能を中心として

概要

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In order to evaluate the cellular immunity of subjects with chyluria, which is a prominent complication of Bancroftian filariasis, T cell counts of the Peripheral blood, lymphocyte blastformation with purified phytohemagglutinin and serum toxoplasma antibody titer were measured, and skin tests with PPD and PHA were performed. The subjects of this study were diagnosed to have filarial chyluria on the basis of epidemiological findings. T cell counts of the patients were reduced on an average to half of those of controls. peripheral blood lymphocytes from the subjects gave responses to a small degree to purified phytohemagglutinin when challenged in vitro in a lymphocyte blastformation assay. Furthermore, all of the peripheral blood lymphocyte counts, T cell counts of the peripheral blood and lymphocyte blastformation were significantly decreased in chyluria patients with positive toxoplasma antibody as compared with those in chyluria patients antibody negative.
長崎大学熱帯医学研究所の論文
1984-09-29