Energy Metabolic Changes during Induced Hyperthermia

概要

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The influence of induced hyperthermia on energy metabolism was investigated by elevating body temperature up to 43℃ with warm water in anesthetized 8 mongrel dogs. This study showed that both the oxygen consumption and carbon dioxide production increased 8-10% for a body temperature rise of one centigrade degree, and also increased about 50% and 40%, respectively at 43℃ although non-protein respiratory quotient was kept constant. Blood glucose level has been kept more than 100g/dl during experiment. On the other hand, both arterial acetoacetate and β-hydroxybutyrate levels increased significantly about 60% and 100%, respectively at 43℃. These results may show that both carbohydrate and fat utilization for energy expenditure tends to be higher during hyperthermia.
長崎大学熱帯医学研究所の論文
1992-06-30