Difference in the Reaction of Peritoneal Cells to Brugia pahangi in Several Strain of Mice
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The difference in the recovery rate of Brugia pahangi and reaction of peritoneal cells among the 5 strains of mice are described in the present study. When intraperitoneal infection was used, the recovery rates at 2 weeks after infection in male mice were 1.8, 9.1, 1.7, 17.0 and 2.3% in C3H/He, C57BL/6, BALB/c ICR and ddy, respectively. The recovery rates in femal mice were 6.8, 3.7, 4.8, 10.8 and 2.4% in C3H/He, C57BL/6, BALB/c, ICR and ddy, respectively. There was a significant difference between males and females in the recovery rates of C3H/He and C57BL/6 (P<0.05). A higher reaction to parasites was recognized in female C57BL/6 and ddy (54.5 and 55.6%). The scanning electron microscope could not reveal remarkable changes on the cuticular surface of worm. The transmission electron microscope showed eosinophils and lymphocytes on the worms surrounded by peritoneal cells.
- 長崎大学熱帯医学研究所の論文
- 1989-09-30
長崎大学熱帯医学研究所 | 論文
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