コレラ菌ファージ型別の応用性に関する研究 : ケニア国分離エルトールコレラ菌の型別
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概要
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A total of 434 strains of Vibrio cholerae biovar eltor (Fig. 1, Table 1) were typed by a set of the typing phages obtained originally from National Institute of Cholera and Enteric Diseases in Calcutta (Table 2) and also tested for the serotype, Takeya's prophage type and hemolytic property. Phage types of 294 strains (67.7%) were decided by the same sensitive patterns after the second typing and 83.6% of the remaining strains were classified as Table 3 after an additional test. Following the forth typing the remaining 23 strains were classified as Table 4. From these results, it was concluded that the reproducibility of the phage typing was good enough to apply. The resulted phage types were summarized in Tables 15 and 16. The results for serotype, prophage type and hemolytic property were as follows: Inaba 48 (11.1%), Ogawa 386 (88.9%); Lysogenic Celebes 369 (85.0%), Cured Celebes 63 (14.5%), Ubol 2 (0.5%); Hemolytic 324 (74.7%), Weakly hemolytic 34 (7.8%), Non-hemolytic 76 (17.5%). The results of four properties were shown in Tables 5-12 by locality and year indicated in Table 1 and the geographical distribution of each property was summarized in Tables 13, 14, 17 and 18. Table 13 shows special distribution of Inaba type in Kisumu with 100% and in South Coast 1982 with 62.1% comparing with other groups where Ogawa type is predominant. In Table 14, all of 60 strains from Kapedo are cured Celebes type while 98.7% of others are lysogenic Celebes type. From Table 17, the followings can be pointed out: 81.7% of strains isolated in Kapedo is Type 1 which is not found in other location. Main phage type of isolates from Nairobi 1982 and South Coast 1981/1982 is Type 4 while other four groups is Type 3. Main phage type in Nairobi has changed between 1980 and 1982. Table 18 indicates that majority of strains isolated in Kenya is hemolytic excepting isolates from Busia in 1980. From these findings, it can be said that the phage typing will give more information than serotype or prophage type for epidemiological observation of cholera.
- 長崎大学熱帯医学研究所の論文
- 1983-06-30
長崎大学熱帯医学研究所 | 論文
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