On Pathogenesis of So-Called "Cerebral Embolism"

概要

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A total of 21 cases diagnosed as "cerebral embolism" at autopsy (softening 9 and hemorrhage 12 cases, having endocarditis or sepsis) were studied in detail in an attempt to clarify the mechanism of softening and hemorrhage. According to the result obtained, mechanical obstruction of an artery by an embolus is not always the cause of "embolic softening", and the "embolic hemorrhage" is not diapedetic, but principally rhexis-bleeding. In both softening and hemorrhage, the chief role is played by some inflammatory agents carried from the heart to the meningeal and/or intracerebral artery and inciding a localized arteritis. When the arteritis undergoes a proliferative or thrombus-forming process, stenosis or obstruction of the vessel and softening occurs, whereas when it undergoes a exsudative or destructive process, rupture and hemorrhage occurs.
Nagasaki University School of Medicineの論文
1962-12-00