Studies on Alterations in Acid Phosphatase Activity, Body Weight and Ultrastructure of Adult Angiostrongylus cantonensis in Rats Treated with Flubendazole at a Subcurative Dose
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Physiological effects of flubendazole on adult Angiostrongylus cantonensis were studied. Administration of flubendazole for 3 consecutive days (48-50 days post-infection) at 10 mg/kg/day did not affect the number of worms of and weight of adult female A. cantonensis recovered from rats 16 hr after termination of medication while it lowered the phosphatase activity by the intact worms. The possible modes of action of the drug were discussed together with electron-microscopic observation of the body wall of the worms recovered from the treated and non-treated rats.
- 長崎大学熱帯医学研究所の論文
- 1998-03-20
長崎大学熱帯医学研究所 | 論文
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