Quantitative Assessment of Relationships between Abdominal Aortic Calcification and Bone Mineral Content of Lumbar Vetebrae in the Elderly by Computed Tomography

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The rerationship between adominalaortic calcification and osteoporosis in 224 elderly patients (82 men, 142 women, age ranged from 60 to 94 yrs [77.8 ± 7.6] ) was investigated by computed tomography. We calculated the aortic calcification index (ACI;%) of calcification volume to aortic volume within 10 slices in the lower abdominal aorta, and measured the bone mineral (BMC;mg/c?) of three lumbar vertebral bodies (the 2nd, 3rd, 4th) using a calibrated phantom. ACI increased, but BMC decreased gradually with aging. ACIs in women were significantly less in the 60s decade age (p<0.01), but higher in the 80s and 90s (NS) than in men. BMCs in women were significantly less than those in men in the 70s and 80s (p<0.01 and p<0.05, respectively). In both the 7os and 80s, there were significant nagative correlations between ACIs and BMCs in women (70s:n=61, r=-0.371,p<0.01; 80s:n=55,r=-0.334,p<0.01), but was no relation between them in men. Theseresults suggested that in the elderly women, abdominal aortic calcification is related to the bone loss caused by postmenopausal osteoporosis.
Yamaguchi University Graduate School of Medicineの論文