Synergetic Effects of Dopamine and High-Dose Bumetanide in Patients with oliguria
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概要
- 論文の詳細を見る
The effects of a combination of dopamine and bumetanide were studied in eight patients with oliguria not responsive to conventional treatment. Dopamine was infused at a rate of 3 чg/kg/min and bumetanide was given as a 0.05-0.1 mg/kg bolus everv 2 hours intravenously. Administration continued for 3 to 15 days. Urine output, blood urea nitrogen, serum creatinine, the ratio of urine to plasma osmolarity, free water clearance, and serum electroiytes were measured before, during, and after the administration period. Six of the eight patients responded with an increase in urine output and improvement of the other variables ; the other two did not. We conclude that the combination of dopamine and high-dose bumetanide is effective in increasing diuresis in critically ill patients in the early stages of oliguria.
- Yamaguchi University Graduate School of Medicineの論文
著者
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Yamashita S
Kurashiki Central Hospital Kurashiki Jpn
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Yokota Kimio
Kobe Shipyard And Machinery Works Mitsubishi Heavy Industries Ltd.
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