Feasibility of Exploiting Celution^<TM> System in Autologous Cell Therapy in Dokkyo Medical University Hospital:Safety and Reproducibility
スポンサーリンク
概要
- 論文の詳細を見る
In 2012, we established the Center for Regenerative Medicine in Dokkyo Medical University Hospital, and are now preparing the necessary equipment and preclinical evidence for cell therapy. Liposuction is a commonly used procedure in plastic surgery and the lipoaspirate is discarded as a medical waste. However, the lipoaspirate is known to contain abundant mesenchymal stem cells, and thus, it is currently one of the most feasible options of regenerative medicine. Several ongoing clinical trials of cell therapy (in Japan and overseas as well) are based on the Celution^ system, an automated cell-processing machine utilizing lipoaspirate. The merit of using such a machine is that collected cells are so abundant that it is not necessary to expand the cell number in a Cell Processing Center. Moreover, there are fewer risks of bacterial infection because the system is isolated from the ambient dust and operated automatically. Our group is now planning respective cell therapies for breast reconstruction after mastectomy, urinary incontinence and ischemic cardiovascular diseases, and all these protocols will be based on the Celution^ system. Here, we report the initial test run of Celution^ to confirm its safety and reproducibility.
- 獨協医科大学の論文
- 2014-03-25
著者
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Akimoto Kazumi
Research Center For Molecular And Cellular Biology Dokkyo University School Ofmedicine
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Nomura Hiroshi
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine:Department Of Plastic And Reconstructive Surgery, Dokkyo Medical University School Of Medicine
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Mitsumori Tomoyuki
Cytori Therapeutics Incorporation:Department Of Cardiovascular Medicine, Dokkyo Medical University School Of Medicine
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Iwaguro Hideki
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine:Cytori Therapeutics Incorporation
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Inoue Ken-ichi
Research Support Center, Dokkyo Medical University School Of Medicine:Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine
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Sohma Ryoichi
Research Support Center, Dokkyo Medical University School Of Medicine
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Kobayashi Naohiko
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine
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Kamai Takao
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine
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Yamanishi Tomonori
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine
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Taguchi Isao
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine
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Asato Hiroki
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine
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Inoue Teruo
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine
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Yoshida Ken-ichiro
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine
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Yoshida Ken-ichiro
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine:Cytori Therapeutics Incorporation
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Yamanishi Tomonori
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine:Department Of Urology, Dokkyo Medical University School Of Medicine
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Taguchi Isao
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine:Department Of Cardiovascular Medicine, Dokkyo Medical University School Of Medicine
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Inoue Teruo
Center For Regenerative Medicine, Dokkyo Medical University School Of Medicine:Department Of Cardiovascular Medicine, Dokkyo Medical University School Of Medicine
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Sohma Ryoichi
Research Support Center, Dokkyo Medical University School Of Medicine:Department Of Plastic And Reconstructive Surgery, Dokkyo Medical University School Of Medicine
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- Feasibility of Exploiting Celution^ System in Autologous Cell Therapy in Dokkyo Medical University Hospital:Safety and Reproducibility