長野県諏訪地域における抗菌薬使用量と耐性菌の検出頻度について

概要

論文の詳細を見る
Objectives: A cross-sectional study was conducted to estimate the amount of antimicrobial usage and to analyze the correlation to resistant bacteria. Methods: Records on antimicrobial prescriptions in the Suwa area of Nagano prefecture, from December 2009 to May 2010, were collected from the electronic database of the national health insurance system. Records on antimicrobial resistant bacteria during the same period were collected from hospitals in the area. These data were compared with the published data from Europe. Results: The target population was 31,505 people (27.1 % of the total population in the area). More antimicrobials were prescribed in outpatient settings rather than inpatient settings. Total antimicrobial usage in outpatient settings was 9.34 DDD (defined daily doses) per 1,000 inhabitant-days. MLS (macrolides, lincosamides, and streptogramins) was the most prescribed drug group, followed by beta-lactams other than penicillin and quinolone. The rate of quinolone-resistance among Escherichia coli in this area was within the predictable range, according to the European data, however, that of macrolide-resistance among Streptococcus pneumoniae exceeded the predictable range. Conclusion: Electronic database of health insurance system is useful to collect data on antimicrobial usage with a view to taking action against antimicrobial resistance including antimicrobial stewardship.
国立保健医療科学院の論文
2011-10-00