A study of double assembly method for DNA sequences

概要

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To derive restored sequence without reference, some assembly algorithms have been proposed. Assembly result depends on assembly algorithm and argument. Because of that, it is difficult to obtain the best result. In this paper, we proposed a double assembly method that combine the results of different k-mers and different assembly algorithms in order to learn about appropriate combining to generate accurate longer sequence. We evaluated it's performance with the length, coverage ratio(cov-R), correct ratio(Cor-R) of contigs and identified effective characteristic parameters to generate accurate longer sequence.
2013-03-14