Antimutagens in Citrus sudachi Hort. et Shirai

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概要

• 論文の詳細を見る

• Antimutagens from Citrus sudachi Hort. et Shirai were examined. A methanol extract prepared from immature green fruit of this plant reduced the mutagenicity of 3-amino-l-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) when Salmonella typhimurium TA98 was used in the presence of a rat liver microsomal fraction. From the methanol extract, two antimutagens were separated chromatographically while monitoring the antimutagenic activity on Trp-P-2 by a plate method of a modified Ames test, and were identified as 5, 7, 4'-trihydroxy-6, 8, 3'-trimethoxyflavone (sudachitin) and 5, 7, 3',4'-tetrahydroxy-6, 8-dimethoxyflavone (3'-demethoxysudachitin).

• 日本生薬学会の論文
• 2000-02-20

著者

• Komai Koichiro

  Laboratory Of Pesticide Chemistry Department Of Agricultural Chemistry Kinki University

• Nakasugi Toru

  Research Laboratory Of Medicinal Products Of Plant Origin Inabata Koryo Co. Ltd.

• Nakashima Mika

  Laboratory of Pesticide Chemistry, Deptartment of Agricultural Chemistry, Kinki University

• Nakashima Mika

  Laboratory Of Pesticide Chemistry Deptartment Of Agricultural Chemistry Kinki University

• Komai Koichiro

  Laboratory Of Pesticide Chemistry Deptartment Of Agricultural Chemistry Kinki University

関連論文

• Plant growth inhibitors : Patchoulane-type sesquiterpenes from Cyperus rotundus L.
• Antimutagens in Citrus sudachi Hort. et Shirai

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