Assembly of a protein "brush" by end-grafting titin fragments to liposomes(BIOCHEMICAL ENGINEERING)

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概要

• 論文の詳細を見る

• Titin is a giant filamentous protein of striated muscle composed of >300 immunoglobulin-like domains linked in tandem. Here, we demonstrate that a six-immunoglobulin fragment of titin carrying a poly-histidine tag forms a protein "brush" on liposomes containing metallochelating lipids. These specimens might allow the direct visualization by cryo-EM of frozen hydrated and unstained titin chains with preserved architectural features.

著者

• Kreplak Laurent

  Department Of Physics And Atmospheric Science Dalhousie University

• Franke Barbara

  Institute Of Integrative Biology University Of Liverpool

• Chami Mohamed

  Center For Cellular Imaging And Nanoanalytics (c-cina) Biozentrum University Of Basel

• Mayans Olga

  Institute of Integrative Biology, University of Liverpool

• Mayans Olga

  Institute Of Integrative Biology University Of Liverpool

関連論文

• Assembly of a protein "brush" by end-grafting titin fragments to liposomes(BIOCHEMICAL ENGINEERING)

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