Biotransformation of quinazoline and phthalazine by Aspergillus niger(ENVIRONMENTAL BIOTECHNOLOGY)
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概要
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Cultures of Aspergillus niger NRRL-599 in fluid Sabouraud medium were grown with quinazoline and phthalazine for 7 days. Metabolites were purified by high-performance liquid chromatography and identified by mass spectrometry and proton nuclear magnetic resonance spectroscopy. Quinazoline was oxidized to 4-quinazolinone and 2,4-quinazolinedione, and phthalazine was oxidized to 1-phthalazinone.
著者
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SUTHERLAND John
National Center for Toxicological Research
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Freeman James
National Center For Toxicological Research U.s. Food And Drug Administration
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Heinze Thomas
National Center For Toxicological Research U.s. Food And Drug Administration
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Schnackenberg Laura
National Center for Toxicological Research, U.S. Food and Drug Administration
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Williams Anna
National Center for Toxicological Research, U.S. Food and Drug Administration
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Sutherland John
National Center For Toxicological Research U.s. Food And Drug Administration
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Williams Anna
National Center For Toxicological Research U.s. Food And Drug Administration
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Schnackenberg Laura
National Center For Toxicological Research U.s. Food And Drug Administration
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Sutherl John
National Center for Toxicological Research, U.S. Food and Drug Administration
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Heinzea Thomas
National Center for Toxicological Research, U.S. Food and Drug Administration
関連論文
- Sample preparation and high-resolution separation of mycotoxins possessing carboxyl groups
- Biotransformation of quinazoline and phthalazine by Aspergillus niger(ENVIRONMENTAL BIOTECHNOLOGY)