746 顕微鏡可視化力学試験機による関節軟骨の円筒部拘束条件の影響(S01-1 細胞と組織のバイオメカニクス(1)-ミクロからマクロまで-,21世紀地球環境革命の機械工学:人・マイクロナノ・エネルギー・環境)

概要

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The purpose of this study is to analyze the compressive behavior of articular cartilage in confined compression. Articular cartilage realizes very low friction and long durability in synovial joint. So, the mechanism and functional behavior of articular cartilage has been observed by many researchers for the insights of arthritic disease, regenerative medicine, and new tribological design. Articular cartilage has high water content of nearly 80% and behaves as biphasic material. To observe the mechanical behavior of articular cartilage, authors developed micro testing machine, which equipped on microscope and had the ability to visualize the strain in tissue. In this report, we constructed a confined compression chamber for the cartilage test piece, and compared the mechanical behavior between unconfined and confined compression. The morphology of subcondral bone was also observed from the view point of fluid transport.
一般社団法人日本機械学会の論文
2008-08-02